YOU KNOW THAT YOU’RE FORGETFUL AND CONFUSED. IT MAY BE TIME TO EXPLORE WHY

Losing your keys. Forgetting someone’s name. Finding yourself confused about a routine task. These may be common signs of normal aging—or they could be signs of thinking or memory issues.

Diagnosing potential causes of thinking or memory issues can be difficult, as many of these conditions have similar symptoms.

To evaluate what might be the problem, your doctor may run a few tests that assess your thinking, memory, and decision-making abilities.

As part of the clinical assessment, your doctor may also ask you to have an imaging test performed that detects whether there is a buildup of a protein called amyloid plaque in your brain.

WHAT IS AMYLOID?

  • Amyloid is a protein that your body produces naturally
  • This protein can clump together and create beta-amyloid plaques, which can block communication between signals in the brain
  • While present in many people, scientists believe that the buildup of amyloid plaques may be associated with thinking or memory problems
  • Amyloid plaques can accumulate for years before you start to experience thinking or memory issues

IN 2012, AMYVID BECAME THE FIRST FDA-APPROVED TEST FOR IMAGING BETA-AMYLOID IN THE BRAIN

Amyvid highlights beta-amyloid plaques that may be present in the brain using a tracer (radioactive fluorine). This is detected during a “PET” scan.

The Amyvid scan will be reviewed to determine whether a large amount of beta-amyloid plaques are present. Your doctor will consider your Amyvid scan results along with those from other tests to help understand the cause of your thinking or memory problems.

Is your Amyvid appointment already set? Prepare for your upcoming appointment with these helpful tips.

EXPLORE TIPS

PET=positron emission tomography.

SELECT SAFETY INFORMATION

  • Errors may happen when Amyvid scan images are read. In clinical studies, a scan read as negative, when it was actually positive, accounted for most of these errors. An Amyvid scan only indicates whether beta-amyloid plaques, which are a buildup of proteins in the brain, are present at the time of the scan. Even if the scan is negative, it is possible to develop plaques in the future.
  • Amyvid, like other radioactive diagnostic agents, adds to overall, long-term combined radiation exposure. Long-term combined radiation exposure may increase risk of cancer.

Important Facts About Amyvid® (am-uh-vid). It is also known as florbetapir F 18.

What is Amyvid used for?
Amyvid is an imaging agent used in adults who have thinking or memory problems and who are being assessed for Alzheimer's Disease (AD) or some other causes of these symptoms. Amyvid is given by injection and it requires a prescription.

Amyvid is used with a machine called a positron emission tomography (PET) scanner. The scan shows whether a person's brain has an abnormal buildup of a protein called beta-amyloid. When beta-amyloid proteins build up and clump together, they form lumps in the brain called plaques.

What is a negative scan?
An Amyvid scan that shows few or no plaques in the brain is called a negative scan. This means that AD is probably not the cause of the person's thinking or memory problems. This is only true as of the time of the scan.

What is a positive scan?
An Amyvid scan that shows a similar amount of plaque as scans from people with AD is called a positive scan. People with other conditions that cause thinking or memory problems as well as older people with normal thinking or memory can also have that amount of plaque in their brain.

Doctors use Amyvid in combination with other tests. A positive Amyvid scan does not mean you definitely have AD or another thinking or memory disorder. Amyvid should not be used to predict dementia or other brain conditions. It also should not be used to track whether a treatment is working.

Warnings

  • Errors may happen when Amyvid scan images are read. In clinical studies, a scan read as negative, when it was actually positive, accounted for most of these errors. An Amyvid scan only indicates whether beta-amyloid plaques, which are a buildup of proteins in the brain, are present at the time of the scan. Even if the scan is negative, it is possible to develop plaques in the future.
  • Amyvid, like other radioactive diagnostic agents, adds to overall, long-term combined radiation exposure. Long-term combined radiation exposure may increase risk of cancer.

Common side effects

  • Headache
  • Muscle or joint pain
  • Higher blood pressure. This is when the force of blood flowing through your blood vessels is too high.
  • Nausea
  • Tiredness
  • Injection site reaction (bleeding, irritation, or pain where Amyvid is injected)

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch .

Before you receive Amyvid

  • Tell your doctor if you are pregnant, breast-feeding, or plan to become pregnant or breastfeed.
  • Tell your doctor about all medicines you take, including prescription and over-the-counter medicines, as well as vitamins and herbal supplements.

How to receive Amyvid

Amyvid should only be given by healthcare professionals who are qualified by specific training and experience in the safe use and handling of radioactive materials safely.

Learn more

For more information, call 1-800-545-5979 or go to amyvid.com.

This summary provides basic information about Amyvid. It does not include all information known about this drug. Read the information given to you about Amyvid before your PET scan. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Amyvid. Your doctor is the best person to help you decide if an Amyvid PET scan is right for you.

Amyvid® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

Please see full Prescribing Information for Amyvid.

AM CON BS 10DEC2021